Document Type : Research Paper
Authors
Faculty of Materials and Metallurgical Engineering, Semnan University, Semnan, Iran.
Abstract
The present study outlines the production of AgNPs through a green synthesis method utilizing the water extract of Ferula assa-foetida leaves. In contrast to earlier studies that mainly focused on the plant's gum, this research used an ultrasonic-assisted extraction method for the leaf tissues. FTIR analysis validated the presence of different organic compounds, particularly phenolic groups, on the AgNPs surface, which is crucial for their stability and bioactivity. FE-SEM images displayed the nanoparticles' shapes, which were mainly spherical and cauliflower-like, with an average size of 86 nm. XRD analysis revealed that silver ions were reduced to create metallic nanoparticles in the following phase, as shown by distinctive peaks at 38.2°, 44.4°, and 64.51°. Synthesized nanoparticles were assessed for antibacterial properties against two bacterial models: Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative). A higher sensitivity was observed in Gram-positive bacteria. Therefore, AgNPs produced using Ferula leaf extract can be considered valuable alternatives for antibacterial and therapeutic purposes.
Keywords
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