Document Type : Research Paper

Authors

1 School of Environment, College of Engineering, University of Tehran, Tehran, Iran.

2 Faculty of Civil & Architectural Engineering, Department of Civil Engineering, Shahrood University of Technology, Shahrood, Iran.

10.22126/arww.2022.6842.1224

Abstract

In this study, the effect of antibiotic wastewater containing 20 common pharmaceuticals (14 antibiotics and 6 non-steroidal anti-inflammatory drugs (NSAIDs)) individually as well as their combination was investigated on activated
sludge in batch reactors. The chemical oxygen demand (COD), the ammonium concentration, the inhibition rate and toxicity index of COD and ammonium were investigated in wastewater. The inhabitation for COD and ammonium removal was variable for each drug so that the pharmaceuticals are applied simultaneously had such a greater adverse effect on inhibition rate than individual compounds. The pretreatment of wastewaters containing drugs was performed by powdered activated carbon PAC to reduce the adverse effect of these drugs on activated sludge. The appropriate method for separation of PAC from wastewater before introducing to activated sludge process and the optimized adsorption and contact time during the pretreatment process were studied. The pretreatment of pharmaceuticals wastewater with activated carbon improved well COD and NH4+ removal to 71 % and 55 %, respectively, that demonstrate the activated carbon can be considered as a suitable pretreatment option for the activated sludge.

Keywords

Altmann J., Ruhl A.S., Zietzschmann F., Jekel M., Direct comparison of ozonation and adsorption onto powdered activated carbon for micropollutant removal in advanced wastewater treatment, Water Research 55 (2014) 185-193.
Angeles L.F., Mullen R.A., Huang I.J., Wilson C., Khunjar W., Sirotkin H.I., McElroy A., E.Aga D.S., Assessing pharmaceutical removal and reduction in toxicity provided by advanced wastewater treatment systems, Environmental Science: Water Research & Technology 6 (2020) 62-77.
Aziz S.Q., Aziz H.A., Yusoff M.S., Bashir M.J., Landfill leachate treatment using powdered activated carbon augmented sequencing batch reactor (SBR) process: Optimization by response surface methodology, Journal of Hazardous Materials 189 (2011) 404-413.
Baird R.B., Eaton A.D., Rice E.W., Bridgewater L., Standard methods for the examination of water and wastewater, American Public Health Association Washington, DC, (2017).
Benstoem F., Nahrstedt A., Boehler M., Knopp G., Montag D., Siegrist H.Pinnekamp J., Performance of granular activated carbon to remove micropollutants from municipal wastewater—A meta-analysis of pilot-and large-scale studies, Chemosphere 185 (2017) 105-118.
Bergeron S., Boopathy R., Nathaniel R., Corbin A., LaFleur G., Presence of antibiotic resistant bacteria and antibiotic resistance genes in raw source water and treated drinking water, International Biodeterioration & Biodegradation 102 (2015) 370-374.
Besha A.T., Gebreyohannes A.Y., Tufa R.A., Bekele D.N., Curcio E., Giorno L., Removal of emerging micropollutants by activated sludge process and membrane bioreactors and the effects of micropollutants on membrane fouling: A review, Journal of Environmental Chemical Engineering 5 (2017) 2395-2414.
Caban M., Stepnowski P., How to decrease pharmaceuticals in the environment? A review, Environmental Chemistry Letters (2021) 1-24.
Dokianakis S., Kornaros M., Lyberatos G., On the effect of pharmaceuticals on bacterial nitrite oxidation, Water Science and Technology 50 (2004) 341-346.
Grandclément C., Seyssiecq I., Piram A., Wong-Wah-Chung P., Vanot G., Tiliacos N., Roche N.Doumenq P., From the conventional biological wastewater treatment to hybrid processes, the evaluation of organic micropollutant removal: a review, Water Research 111 (2017) 297-317.
Gulkowska A., Leung H. W., So M. K., Taniyasu S., Yamashita N., Yeung L. W., Richardson B. J., Lei A., Giesy J. P.Lam P. K., Removal of antibiotics from wastewater by sewage treatment facilities in Hong Kong and Shenzhen, China, Water Research 42 (2008) 395-403.
Guo J., Li J., Chen H., Bond P. L.Yuan Z., Metagenomic analysis reveals wastewater treatment plants as hotspots of antibiotic resistance genes and mobile genetic elements, Water Research 123 (2017) 468-478.
Hernando M.D., Mezcua M., Fernández-Alba A.R., Barceló D., Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments, Talanta 69 (2006) 334-342.
Hirsch R., Ternes T., Haberer K., Kratz K.L., Occurrence of antibiotics in the aquatic environment, Science of The Total Environment 225 (1999) 109-118.
Hu J., Zhou J., Zhou S., Wu P., Tsang Y.F., Occurrence and fate of antibiotics in a wastewater treatment plant and their biological effects on receiving waters in Guizhou, Process Safety and Environmental Protection 113 (2018) 483-490.
Hu Q.Y., Li M., Wang C., Ji M., Influence of powdered activated carbon addition on water quality, sludge properties, and microbial characteristics in the biological treatment of commingled industrial wastewater, Journal of Hazardous Materials 295 (2015) 1-8.
Jafari Kang A., Baghdadi M., Pardakhti A., Removal of cadmium and lead from aqueous solutions by magnetic acid-treated activated carbon nanocomposite, Desalination and Water Treatment 57 (2016) 18782-18798.
Jamialahmadi N., Rahimi S., Esmaeili A., Hospital wastewater in Iran: a systematic review and challenges for proper management during coronavirus disease (2019) pandemic, Journal of Applied Research in Water and Wastewater 8 (2021) 59-65.
Kanakaraju D., Glass B.D., Oelgemöller M., Advanced oxidation process-mediated removal of pharmaceuticals from water: a review, Journal of Environmental Management 219 (2018) 189-207.
Kargi F.Pamukoglu M.Y., Powdered activated carbon added biological treatment of pre-treated landfill leachate in a fed-batch reactor, Biotechnology Letters 25 (2003) 695-699.
Kim S., Eichhorn P., Jensen J. N., Weber A.S., Aga D.S., Removal of antibiotics in wastewater: effect of hydraulic and solid retention times on the fate of tetracycline in the activated sludge process, Environmental Science & Technology 39 (2005) 5816-5823.
Knopp G., Prasse C., Ternes T.A., Cornel P., Elimination of micropollutants and transformation products from a wastewater treatment plant effluent through pilot scale ozonation followed by various activated carbon and biological filters, Water Research 100 (2016) 580-592.
Kümmerer K., Antibiotics in the aquatic environment–a review–part I, Chemosphere 75 (2009) 417-434.
Kümmerer K., Antibiotics in the aquatic environment–a review–part II, Chemosphere 75 (2009) 435-441.
Larsson D.J., Antibiotics in the environment, Upsala Journal of Medical Sciences 119 (2014) 108-112.
Li B., Zhang T., Biodegradation and adsorption of antibiotics in the activated sludge process, Environmental Science & Technology 44 (2010) 3468-3473.
Li Y., Liu Y., Tang J., Lin H., Yao N., Shen X., Deng C., Yang P.Zhang X., Fe3O4@ Al2O3 magnetic core–shell microspheres for rapid and highly specific capture of phosphopeptides with mass spectrometry analysis, Journal of Chromatography A 1172 (2007) 57-71.
Louvet J.N., Giammarino C., Potier O.Pons M.N., Adverse effects of erythromycin on the structure and chemistry of activated sludge, Environmental Pollution 158 (2010) 688-693.
Magureanu M., Mandache N. B.Parvulescu V.I., Degradation of pharmaceutical compounds in water by non-thermal plasma treatment, Water Research 81 (2015) 124-136.
Meinel F., Zietzschmann F., Ruhl A., Sperlich A.Jekel M., The benefits of powdered activated carbon recirculation for micropollutant removal in advanced wastewater treatment, Water Research 91 (2016) 97-103.
Nayeri D., Mousavi S.A., Mehrabi A., Oxytetracycline removal from aqueous solutions using activated carbon prepared from corn stalks, Journal of Applied Research in Water and Wastewater 6 (2019) 67-72.
Östman M., Lindberg R.H., Fick J., Björn E.Tysklind M., Screening of biocides, metals and antibiotics in Swedish sewage sludge and wastewater, Water Research 115 (2017) 318-328.
Park S.J., Oh J.W., Yoon T.I., The role of powdered zeolite and activated carbon carriers on nitrification in activated sludge with inhibitory materials, Process Biochemistry 39 (2003) 211-219.
Quintelas C., Mesquita D.P., Torres A.M., Costa I.Ferreira E.C., Degradation of widespread pharmaceuticals by activated sludge: Kinetic study, toxicity assessment, and comparison with adsorption processes, Journal of Water Process Engineering 33 (2020) 101061.
Rivera-Utrilla J., Sánchez-Polo M., Ferro-García M.Á., Prados-Joya G.Ocampo-Pérez R., Pharmaceuticals as emerging contaminants and their removal from water, A review, Chemosphere 93 (2013) 1268-1287.
Satyawali Y., Balakrishnan M., Performance enhancement with powdered activated carbon (PAC) addition in a membrane bioreactor (MBR) treating distillery effluent, Journal of Hazardous Materials 170 (2009) 457-465.
Shokrolahi S., Farhadian M.Davari N., Degradation of Enrofloxacin antibiotic in contaminated water by ZnO/Fe2O3/Zeolite nanophotocatalyst, Journal of Applied Research in Water and Wastewater 6 (2019) 150-155.
Watkinson A., Murby E.Costanzo S., Removal of antibiotics in conventional and advanced wastewater treatment: implications for environmental discharge and wastewater recycling, Water Research 41 (2007) 4164-4176.
Wollenberger L., Halling-Sørensen B, Kusk K.O., Acute and chronic toxicity of veterinary antibiotics to Daphnia magna, Chemosphere 40 (2000) 723-730.
Zhang T., Li B., Occurrence, transformation, and fate of antibiotics in municipal wastewater treatment plants, Critical Reviews in Environmental Science and Technology 41 (2011) 951-998.